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Information and Services for Medical Professionals

Please note that Iscador AG will not assume any responsibility for the access of information, which may not agree with the legislation or registration applicable in your country of residence.

Integrative Oncology with Mistletoe

Mistletoe preparations for subcutaneous injections have been an important part of integrative cancer treatment for many decades. They are used additionally to conventional cancer treatment to improve quality of life, reduce side effects and prevent tumour recurrence.

Each preparation has its own characteristics and should only be applied by trained medical professionals. In Switzerland, ISCADOR preparations need to be prescribed by a medical professional, whereas in Germany, they are available in pharmacies without prescription. Please check the regulations about mistletoe preparations in your country.

Information material:
 

A large number of clinical studies in various tumour entities are available on mistletoe therapy with ISCADOR. The advantages of an ISCADOR therapy are:

✓ Improvement of quality of life and therapy adherence of tumour patients with conventional oncological therapies by reducing nausea, vomiting, pain and cancer-related fatigue (1,2)

✓ No reported interactions with common oncological pharmacotherapies (3-8)

✓ Part of national and international guideline recommendations (9)

  • AGO guideline on “diagnostics and therapy of early and advanced breast cancer” (Germany): “Can” recommendation for mistletoe therapy with the aim to reduce therapy-related side effects of ongoing oncological standard treatments (Oxford Evidence Level 1a, Oxford Recommendation Level B).
  • Society for Integrative Oncology (SIO) and American Society of Clinical Oncology (ASCO): “Can” recommendation (grade C) for subcutaneous mistletoe therapy. It can thus be used to improve the quality of life of cancer patients.
  • S3 guideline “Complementary medicine in the treatment of oncological patients” issued by the Working Group of the German Scientific Medical Societies (AWMF e. V.): Can” recommendation with the aim of improving quality of life of cancer patients (Level of Evidence 1a)

✓ More clinical and scientific information on www.mistletoe-therapy.org/

 

Literature

1. Loef M and Walach H: Quality of life in cancer patients treated with mistletoe: a systematic review and meta-analysis. BMC Complementary Medicine and Therapies 20, 227 (2020)
2. Pelzer F et al.: Cancer-related fatigue in patients treated with mistletoe extracts: a systematic review and meta-analysis. Support Care Cancer 30, 6405 (2022)
3. Schad F et al.: Safety of combined treatment with monoclonal antibodies and Viscum album L. preparations. Integrative Cancer Therapies 1–11 (2016)
4. Thronicke A et al.: Clinical safety of combined therapy of immune checkpoint inhibitors and Viscum album L. therapy in patients with advanced or metastatic cancer. BMC Complementary and Alternative Medicine 17, 534 (2017)
5. Thronicke A et al.: Clinical Safety of Combined Targeted and Viscum album L. Therapy in Oncological Patients. Medicines 5, 100 (2018)
6. Weissenstein U et al.: Interaction of standardized mistletoe (Viscum album) extracts with chemotherapeutic drugs regarding cytostatic and cytotoxic effects in vitro. BMC Complementary and Alternative Medicine 14, 6 (2014)
7. Weissenstein U et al.: Interaction of a standardized mistletoe (Viscum album) preparation with antitumor effects of Trastuzumab in vitro. BMC Complementary and Alternative Medicine 16, 271 (2016)
8. Weissenstein U et al.: Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro. BMC Complementary and Alternative Medicine 19, 23 (2019)
9. https://www.mistletoe-therapy.org/scientific-information/mistletoe-therapy-in-oncological-guidelines

Our mistletoe products are available in many countries all over the world. In our distribution list, you can find our partners in your area:
ISCADOR Distributors worldwide

 

In case your country is not listed, please contact your local pharmacy. They might be able to order some or all of our products through an international pharmacy.

Our Infoline team is at your service:

  • for professional inquiries regarding the use of our products
  • for medical-scientific consultation
  • for reports on adverse reactions (pharmacovigilance)


Get in touch:

E-mail: infoline@iscador.com
Telephone (MON, TUE, THU: 9:00 am – 16:00 pm CET; WED, FRI: 9:00 am – 14:00 pm CET)

  • Austria, France, Italy, New Zealand, Sweden, UK (free of charge): 00800 706 70000
  • All other countries: +49 7621 162 26 00


For individual treatment recommendations, please provide us all data in the Therapy Recommendation Request Form.

Events

In our calendar, professionals can find selected online trainings, face-to-face seminars and other events related to integrative cancer therapy. Sign up, participate and share ideas with your colleagues. Public events are also listed here. Please be aware that most of the events take place in Germany or Switzerland, and therefore are held in German. But every now and then, we also support international events.